Cancer
IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases
Spine InstituteWhat is the purpose of this study?
The purpose of the study is to determine the recurrence rates and survival of patients with clinical T1-2N0 ER+/Her2- invasive breast cancer who have biopsy proven image detected nodal disease treated with upfront lumpectomy or mastectomy with TAD followed by adjuvant therapy. This is a prospective, single arm phase II clinical trial. Patients will be screened and enrolled per eligibility criteria. Patient, tumor, and treatment data will be documented.
Eligibility
- Women age ≥ 45
- Clinical T1-2N0 ER+ invasive breast cancer
- US detected biopsy proven axillary nodal disease
- Written informed consent obtained from subject and ability for subject to comply with the requirements of the study.
- Palpable nodes on physical exam
- Her2+ or ER- invasive breast cancer
- Extranodal extension > 3 mm on nodal biopsy
- More than 2 suspicious nodes on preoperative imaging
Where can I participate?
More about this Clinical TrialWhat is the full name of this Clinical Trial?
IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Clinical T1-2N0 ER+ Her2- Breast Cancer With Ultrasound Detected Nodal Metastases
- Disease Type/ConditionBreast Cancer With Nodal Metastases
- Principal InvestigatorBob Jameson
- Co-InvestigatorsSarah Towns, Clark Kent
- Age GroupAdult, Older Adult
- PhaseII
- IRB NumberSTUDY06092892
- ClinicalTrials.gov IDNCT06092892
- Key Eligibilityclinicaltrials.gov
- How do I learn more about this study?Clinical Trial Recruitment
CancerTrialInformation@hoag.org
Digestive Health Institute

More Digestive Health Trials
(Elacestrant Versus Standard Endocrine Therapy in Early Breast Cancer With High Risk of Recurrence) Elacestrant Versus Standard Endocrine Therapy in Early Breast Cancer With High Risk of Recurrence
(Lung) Lung
(Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors) Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors